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Item number: Cay16419-1

In humans, two forms of diacylglycerol lipase, DAGLalpha and DAGLbeta, generate the endocannabinoid 2-arachidonoyl glycerol (2-AG, Cay-62160) by attacking DAG at the sn-1 position. LEI-106 is a potent in vitro inhibitor of sn-1 DAGLalpha (IC50 = 18 nM). It blocks the hydrolysis of sn-1-oleoyl-2-AG, the natural...

Keywords:	N-[(3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-6-yl)sulfonyl]-N-[(4-phenoxyphenyl)methyl]-glycine
Application:	DAGLalpha inhibitor
CAS	1620582-23-1
MW:	481.6 D

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