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LEI-106
Item number: TGM-T27811-10mg
Description: LEI-106, a novel potent sn-1 DAGLalpha inhibitor, blocks the hydrolysis of sn-1-oleoyl-2-AG, inhibits the hydrolysis of 2-AG by the monoacylglycerol lipase ABHD6. Target: Others. Smiles: CC1(C)OC=2C(=CC(S(N(CC3=CC=C(OC4=CC=CC=C4)C=C3)CC(O)=O)(=O)=O)=CC2)CC1. References: Janssen FJ, Deng H, Baggelaar MP,...
| Application: | DAGLalpha inhibitor |
| CAS | 1620582-23-1 |
| MW: | 481.56 D |
From 110.00€
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LEI-106
Item number: Cay16419-1
In humans, two forms of diacylglycerol lipase, DAGLalpha and DAGLbeta, generate the endocannabinoid 2-arachidonoyl glycerol (2-AG, Cay-62160) by attacking DAG at the sn-1 position. LEI-106 is a potent in vitro inhibitor of sn-1 DAGLalpha (IC50 = 18 nM). It blocks the hydrolysis of sn-1-oleoyl-2-AG, the natural...
| Keywords: | N-[(3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-6-yl)sulfonyl]-N-[(4-phenoxyphenyl)methyl]-glycine |
| Application: | DAGLalpha inhibitor |
| CAS | 1620582-23-1 |
| MW: | 481.6 D |
From 61.00€
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