2 products were found matching "1620278-72-9"!

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Item number: TGM-T5561-100mg

Description: TLR7/8 agonist 1 dihydrochloride (TLR7/8 agonist-5d) is a TLR7/8 agonist which shows prominent immunostimulatory activities. Target: TLR. Smiles: Cl.Cl.CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(CN)cc1. References: Shukla NM, et al. Syntheses of fluorescent imidazoquinoline conjugates as probes of Toll-like...

Keywords:	TLR7/8 agonist-5d
Application:	Dual toll-like receptor 7/8 agonist
CAS	1620278-72-9
MW:	432.39 D

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TLR7/8 Agonist 1 (hydrochloride)

Item number: Cay28451-1

TLR7/8 agonist 1 is a dual agonist of toll-like receptor 7 (TLR7) and TLR8 (EC50s = 50 and 55 nM, respectively, in cell-based assays). It increases the levels of TNF-alpha, IFN-gamma, IL-12p40, and chemokine (C-C motif) ligand 4 (CCL4) in human peripheral blood mononuclear cells (PBMCs) in a biphasic manner. TLR7/8...

Keywords:	1-[[4-(aminomethyl)phenyl]methyl]-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine, dihydrochloride
Application:	Dual toll-like receptor 7/8 agonist
CAS	1620278-72-9
MW:	432.4 D

From 98.00€ *

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