- Search results for 1619903-54-6
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2 products were found matching "1619903-54-6"!
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Item number: TGM-TQ0060-100mg
Description: LY2857785 is a type I competitive and reversible ATP kinase inhibitor against CDK7/CDK8/CDK9 (IC50s: 246 nM/16 nM/11 nM). Target: CDK, Apoptosis. Smiles: CC(C)c1n(C)nc2ccc(cc12)-c1ccnc(N[C@H]2CC[C@@H](CC2)NC2CCOCC2)n1. References: Yin T, et al. A novel CDK9 inhibitor shows potent antitumor efficacy in...
Application: | Cdk9 inhibitor |
CAS | 1619903-54-6 |
MW: | 448.6 D |
From 48.00€
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Item number: Cay34880-1
LY2857785 is an inhibitor of cyclin-dependent kinase 9 (Cdk9, IC50 = 0.011 µM). It also inhibits Cdk8 and Cdk7 (IC50s = 0.016 and 0.246 µM, respectively), as well as five kinases in a panel of 114 kinases (IC50s = 50 values of 0.22 and 0.197 µM, respectively. It inhibits phosphorylation of DNA-dependent RNA...
Keywords: | trans-N1-[4-[2-methyl-3-(1-methylethyl)-2H-indazol-5-yl]-2-pyrimidinyl]-N4-(tetrahydro-2H-pyran-4-yl)-1,4-cyclohexanediamine |
Application: | Cdk9 inhibitor |
CAS | 1619903-54-6 |
MW: | 448.6 D |
From 35.00€
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