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EPZ015666
Item number: TGM-T6076-100mg
Description: EPZ015666 (GSK3235025) is an orally available inhibitor of PRMT5 enzymatic activity. Target: Histone Methyltransferase. Smiles: O[C@@H](CNC(=O)c1cc(NC2COC2)ncn1)CN1CCc2ccccc2C1. References: Penebre et al. Epizyme, Inc.
| Keywords: | GSK3235025 |
| Application: | PRMT5 inhibitor |
| CAS | 1616391-65-1 |
| MW: | 383.44 D |
From 42.00€
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EPZ015666
Item number: Cay17285-1
Protein arginine methyltransferases (PRMTs) target nuclear and cytoplasmic substrates and can alter protein actions and gene expression. PRMT5, which can methylate histones H2A, H3, and H4, ribonucleoproteins, and other proteins, is upregulated in several human cancers, including lymphomas. Moreover, suppression of...
| Keywords: | GSK3235025, N-[(2S)-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-hydroxypropyl]-6-(3-oxetanylamino)-4-pyrimidinecarboxamide |
| Application: | PRMT5 inhibitor |
| CAS | 1616391-65-1 |
| MW: | 383.4 D |
From 67.00€
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EPZ015666
Item number: SYN-3044-M001
Off-white solid. Soluble in 100% ethanol (1 mg/ml) or DMSO (10 mg/ml), insoluble in water. Dynamin-1, -2 (DNM1, DNM2) and Dynamin-related protein 1 (DRP1) inhibitor, Endocytosis inhibitor, Viral infection inhibitor, Destabilizes actin filaments, Inhibits entry of Trypanosoma into macrophages, Inhibitor of mitophagy,...
| Keywords: | 3-Hydroxy-naphthalene-2-carboxylic acid (3,4-dihydroxy-benzyl-idene)-hydrazide . 0.5H2O |
| CAS | 1616391-65-1 |
From 123.00€
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