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PCO371
PCO371

Item number: TGM-T16442-10mg

Description: PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-) is an orally active full agonist of parathyroid hormone receptor 1. It has no effect on PTH type 2 receptor. Target: Thyroid hormone...
Keywords: 2,4-Imidazolidinedione,...
Application: PTH1R agonist
CAS 1613373-33-3
MW: 635.65 D
From 97.00€ *
Review
PCO371
PCO371

Item number: Cay39182-1

PCO371 is a parathyroid hormone receptor type 1 (PTH1R) agonist. It selectively induces cAMP production in COS-7 cells expressing human PTH1R (EC50 = 2.4 µM) over COS-7 cells expressing human PTH2R (EC50 = > 100 µM). PCO371 (1 and 3 µM) induces calcium release from isolated fetal rat long bones. It increases lumbar...
Keywords: 1-[3,5-dimethyl-4-[2-[[4-oxo-2-[4-(trifluoromethoxy)phenyl]-1,3,8-triazaspiro[4.5]dec-1-en-8-yl]sulfonyl]ethyl]phenyl]-5,5...
Application: PTH1R agonist
CAS 1613373-33-3
MW: 635.7 D
From 99.00€ *
Review