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Item number: TGM-T12575-100mg

Description: Unesbulin (PTC596) is an orally active, selective inhibitor of B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1). Target: Apoptosis, BMI-1. Smiles: Cc1nc2ccc(F)cc2n1-c1nc(N)c(F)c(Nc2ccc(cc2)C(F)(F)F)n1. References: Nishida Y, et al. The novel BMI-1 inhibitor PTC596 downregulates...

Keywords:	PTC596
Application:	Targets polycomb group RING finger protein 4 (PCGF4, BMI1)
CAS	1610964-64-1
MW:	420.34 D

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PTC-596

Item number: Cay33529-1

PTC-596 is an inhibitor of B cell-specific Moloney murine leukemia virus integration site 1 (BMI1), which is a member of the polycomb repressive complex 1 (PRC1) that has a role in gene silencing. It inhibits proliferation of MOLM-13 acute myeloid leukemia (AML) and Rec-1 mantle cell lymphoma (MCL) cancer cells...

Keywords:	Unesbulin, 5-fluoro-2-(6-fluoro-2-methyl-1H-benzimidazol-1-yl)-N4-[4-(trifluoromethyl)phenyl]-4,6-pyrimidinediamine
Application:	BMI1 inhibitor
CAS	1610964-64-1
MW:	420.3 D

From 108.00€ *

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