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Item number: Cay34075-1

BPN14770 is an inhibitor of phosphodiesterase 4D (PDE4D). It selectively inhibits dimeric PDE4DS129D and PDE4DS54D, which mimic the phosphorylated, activated forms of PDE4D, over wild-type dimeric PDE4D, dimeric PDE4DS133D, and monomeric PDE4D2 (IC50s = 7.8, 7.4, 1,018, 2,013, and 127 nM, respectively). BPN14770...

Keywords:	Zatolmilast, 4-[[2-(3-chlorophenyl)-6-(trifluoromethyl)-4-pyridinyl]methyl]-benzeneacetic acid
Application:	PDE4D inhibitor
CAS	1606974-33-7
MW:	405.8 D

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