- Search results for 159351-69-6
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10 products were found matching "159351-69-6"!
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Item number: TGM-T1784-10mg
Description: Everolimus (SDZ-RAD) is a potent mTOR inhibitor that binds to FKBP-12. It is used alone or in combination with calcineurin inhibitors. Target: Others, Autophagy, mTOR, Apoptosis. Smiles:...
Keywords: | SDZ-RAD, RAD001 |
Application: | Targets serine/threonine-protein kinase mTOR [EC:2.7.11.1] (MTOR, FRAP, TOR) |
CAS | 159351-69-6 |
MW: | 958.22 D |
From 37.00€
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Item number: Cay11597-5
The mammalian target of rapamycin (mTOR) is a serine/threonine kinase that, as part of two distinct complexes (mTORC1 and mTORC2), plays pivotal roles in intracellular signaling. Everolimus is a hydroxyethyl ether rapamycin (Cay-13346) derivative that inhibits mTOR signaling through both mTORC1 and mTORC2 when added...
Keywords: | RAD001, 42-O-(2-hydroxyethyl)-rapamycin |
Application: | mTOR inhibitor |
CAS | 159351-69-6 |
MW: | 958.2 D |
From 66.00€
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Item number: AG-CN2-0520-M001
White to off-white solid. Soluble in DMSO (50mg/ml), ethanol (50mg/ml), methanol or DMF. Insoluble in water. Chemical. CAS: 159351-69-6. Formula: C53H83NO14. MW: 958.2. Isolated from Streptomyces hygroscopicus. Macrolide antibiotic, inhibiting bacterial protein synthesis. Orally available Rapamycin derivative that...
Keywords: | 42-O-(2-Hydroxyethyl)rapamycin, NVP-RAD001, RAD001, SDZRAD, Zortress, Afinitor, Certican, Votubia |
CAS | 159351-69-6 |
MW: | 958,2 D |
From 36.00€
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Item number: E9002-35.5
Everolimus is an immunosuppressant analog of rapamycin (sirolimus) and inhibits growth factor-mediated proliferation of hematopoietic and nonhematopoietic cells. Everolimus shows a potent inhibitory effect on posttransplant lymphoproliferative disorder (PTLD)-derived cells in vitro and in vivo, in a dose range that...
CAS | 159351-69-6 |
MW: | 958.22 |
From 196.00€
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Item number: CDX-E0074-M100
White to off-white solid. Soluble in DMSO (50mg/ml), ethanol (50mg/ml), methanol or DMF. Insoluble in water. Chemical. CAS: 159351-69-6. Formula: C53H83NO14. MW: 958.2. Isolated from Streptomyces hygroscopicus. Macrolide antibiotic, inhibiting bacterial protein synthesis. Potent immunosuppressant. Binds with high...
Keywords: | 42-O-(2-Hydroxyethyl)rapamycin, NVP-RAD001, RAD001, SDZRAD, Zortress, Afinitor, Certican, Votubia |
CAS | 159351-69-6 |
MW: | 958,2 D |
From 597.00€
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Item number: CDX-E0574-M001
Liquid. Chemical. CAS: 159351-69-6. Formula: C53H83NO14. MW: 958.22. Macrolide antibiotic, inhibiting bacterial protein synthesis. Potent immunosuppressant. Binds with high affinity to the FK506 binding protein-12 (FKBP-12) to generate an immunosuppressive complex that inhibits the activation of the mammalian...
Keywords: | 42-O-(2-Hydroxyethyl)rapamycin, NVP-RAD001, RAD001, SDZRAD, Zortress, Afinitor, Certican, Votubia |
CAS | 159351-69-6 |
MW: | 958,22 D |
230.00€
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Item number: ISO-14001UNL.10
Keywords: | unlabelled |
Application: | Mammalian target of rapamycin (mTOR) inhibitor |
CAS | 159351-69-6 |
MW: | 958 D |
Please request pricing for this article.
Item number: ISO-S14001.100
Isotope Incorporation: >98%
Keywords: | Deuterium-labelled, CAS of labelled compound: 1338452-54-2 |
Application: | Mammalian target of rapamycin (mTOR) inhibitor, LC/MS internal standard |
CAS | 159351-69-6 |
Please request pricing for this article.
Item number: ISO-S14001UNL.100
Keywords: | unlabelled |
Application: | Mammalian target of rapamycin (mTOR) inhibitor |
CAS | 159351-69-6 |
MW: | 958 D |
Please request pricing for this article.