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Item number: TGM-T12148-100mg

Description: N-Desmethyltamoxifen hydrochloride is the primary metabolite of tamoxifen in humans. Target: Endogenous Metabolite, PKC, Estrogen Receptor/ERR. Smiles: Cl.CC\C(=C(/c1ccccc1)c1ccc(OCCNC)cc1)c1ccccc1

Application:	Tamoxifen active metabolite
CAS	15917-65-4
MW:	393.95 D

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N-Desmethyltamoxifen (hydrochloride)

Item number: Cay40673-10

N-Desmethyltamoxifen is an active metabolite of the estrogen receptor antagonist tamoxifen (Cay-13258, Cay-11629). It is formed from tamoxifen by the cytochrome P450 (CYP) isoforms CYP2D6, CYP2C19, CYP3A5, or CYP3A4. N-Desmethyltamoxifen is an inhibitor of PKC (IC50 = 8 µM for the rat enzyme). It decreases iron...

Keywords:	2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N-methyl-ethanamine
Application:	Tamoxifen active metabolite
CAS	15917-65-4
MW:	394 D

From 187.00€ *

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