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N-Desmethyltamoxifen (hydrochloride)
N-Desmethyltamoxifen (hydrochloride)

Item number: Cay40673-10

N-Desmethyltamoxifen is an active metabolite of the estrogen receptor antagonist tamoxifen (Cay-13258, Cay-11629). It is formed from tamoxifen by the cytochrome P450 (CYP) isoforms CYP2D6, CYP2C19, CYP3A5, or CYP3A4. N-Desmethyltamoxifen is an inhibitor of PKC (IC50 = 8 µM for the rat enzyme). It decreases iron...
Keywords: 2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N-methyl-ethanamine
Application: Tamoxifen active metabolite
CAS 15917-65-4
MW: 394 D
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