Description: 1-Methyladenosine (M1A) belongs to the class of organic compounds known as purine nucleosides. Target: Endogenous Metabolite. Smiles: Cn1cnc2n(cnc2c1=N)[C@H]1O[C@@H](CO)[C@H](O)[C@@H]1O. References: Hauenschild R, et al. The reverse transcription signature of N-1-methyladenosine in RNA-Seq is sequence...

1-Methyladenosine is a modified nucleoside generated by the processing of tRNA by methyltransferases. The urinary excretion of 1-methyladenosine is elevated in several forms of cancer, supporting its use as a biomarker in early detection. It can also be monitored in serum. Urinary levels of 1-methyladenosine also...