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Item number: TGM-T62381-2mg

Description: Branaplam (LMI070, NVS-SM1) hydrochloride is a selective, orally active SMN2 splicing modulator that acts on SMN (EC50: 20 nM) and inhibits hERG (IC50: 6.3 µM). In a mouse model of severe spinal muscular atrophy (SMA), Branaplam hydrochloride increased full-length SMN protein and improved survival....

Application:	Targets survival motor neuron protein (SMN)
CAS	1562338-39-9
MW:	429.95 D

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