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Item number: Cay29544-10

Dehydrolithocholic acid is a major metabolite of lithocholic acid (LCA, Cay-20253). It is formed from LCA by the cytochrome P450 (CYP) isoform CYP3A4. Dehydrolithocholic acid is an agonist of G protein-coupled bile acid activated receptor 1 (GP-BAR1/TGR5, EC50 = 0.27 µM), vitamin D receptor (VDR, EC50 = 3 µM), and...

Keywords:	3-Ketolithocholic Acid, 3-oxo Lithocholic Acid, 3-oxoLCA, (5beta)-3-oxo-cholan-24-oic acid
Application:	Major lithocholic acid metabolite, TGR5 / VDR / FXR agonist
CAS	1553-56-6
MW:	374.6 D

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