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SB 204990
Item number: TGM-T16861-100mg
Description: SB 204990 is an effective and specific ATP citrate lyase enzyme inhibitor. Target: ATP Citrate Lyase. Smiles: OC(=O)C[C@@]1(O)C[C@@H](CCCCCCc2ccc(Cl)cc2Cl)OC1=O. References: Shares BH, et al. Active mitochondria support osteogenic differentiation by stimulating beta-catenin acetylation. J Biol Chem....
| Application: | ATP-citrate synthase (ACLY) inhibitor |
| CAS | 154566-12-8 |
| MW: | 389.27 D |
From 41.00€
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SB 204990
Item number: Cay15245-1
SB 204990 is a cell-permeable prodrug form of SB 201076, an inhibitor of ATP citrate lyase. SB 204990 inhibits fatty acid and cholesterol synthesis in HepG2 cells in a concentration-dependent manner. Oral administration of SB 204990 (25 mg/kg) reduces plasma levels of the lipoproteins VLDL, LDL, and HDL by 21, 40,...
| Keywords: | (3R,5S)-rel-5-[6-(2,4-dichlorophenyl)hexyl]tetrahydro-3-hydroxy-2-oxo-3-furanacetic acid |
| Application: | ATP-citrate synthase (ACLY) inhibitor |
| CAS | 154566-12-8 |
| MW: | 389.3 D |
From 61.00€
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SB204990
Item number: AG-CR1-3697-M005
White to off-white powder. Soluble in DMSO, ethanol or DMF. Chemical. CAS: 154566-12-8. Formula: C18H22Cl2O5. MW: 389.3. Potent ATP citrate lyase (ACLY) inhibitor. ATP citrate lyase (ACLY), a key enzyme for lipid synthesis, is frequently overexpressed or activated in cancer to promote lipid synthesis and tumor...
| Keywords: | (3R,5S)-rel-5-[6-(2,4-Dichlorophenyl)hexyl]tetrahydro-3-hydroxy-2-oxo-3-furanacetic acid, SB-204990 |
| CAS | 154566-12-8 |
| MW: | 389,3 D |
From 55.00€
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