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Item number: TGM-T17180-100mg

Description: TVB-3166 induces apoptosis and inhibits in-vivo xenograft tumor growth. TVB-3166 is a reversible and selective fatty acid synthase inhibitor (IC50s: 42 nM and 81 nM for biochemical FASN and cellular palmitate synthesis, respectively). Target: Apoptosis, Fatty Acid Synthase, Others. Smiles:...

Application:	FASN inhibitor
CAS	1533438-83-3
MW:	384.47 D

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TVB-3166

Item number: Cay33533-1

TVB-3166 is an inhibitor of fatty acid synthase (FASN, IC50 = 0.042 µM). It inhibits the biosynthesis of palmitate (Cay-10010279) in Calu-6 non-small cell lung cancer (NSCLC) cells and MRC-5 lung fibroblasts in a concentration-dependent manner. TVB-3166 (0.2 µM) induces apoptosis in Calu-6, as well as 22Rv1 prostate...

Keywords:	4-[1-[5-(4,5-dimethyl-1H-pyrazol-3-yl)-2,4-dimethylbenzoyl]-3-azetidinyl]-benzonitrile
Application:	FASN inhibitor
CAS	1533438-83-3
MW:	384.5 D

From 47.00€ *

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