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Item number: TGM-T4347-100mg

Description: ML355, a specific, effective 12-Lipoxygenase(12-LOX) inhibitors(IC50=0.34 µM), possess favorable ADME properties. Target: Lipoxygenase. Smiles: COc1cccc(CNc2ccc(cc2)S(=O)(=O)Nc2nc3ccccc3s2)c1O. References: Luci DK, et al. Synthesis and structure-activity relationship studies of...

Application:	12-LO inhibitor
CAS	1532593-30-8
MW:	441.52 D

From 42.00€ *

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ML-355

Item number: Cay18537-1

Platelet-type 12-lipoxygenase (12-LO, Cay-10341) catalyzes the formation of 12-HpETE (Cay-44570) from arachidonic acid (Cay-90010). It has been found to be expressed in various tumor cells as well as pancreatic islets and can be activated by inflammatory cytokines. It has also been implicated in the modulation of...

Keywords:	N-2-benzothiazolyl-4-[[(2-hydroxy-3-methoxyphenyl)methyl]amino]-benzenesulfonamide
Application:	12-LO inhibitor
CAS	1532593-30-8
MW:	441.5 D

From 66.00€ *

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