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Item number: TGM-T4976-100mg

Description: Umbralisib (TGR 1202) is a PI3Kdelta inhibitor. Target: PI3K. Smiles: CC(C)Oc1ccc(cc1F)-c1nn([C@@H](C)c2oc3ccc(F)cc3c(=O)c2-c2cccc(F)c2)c2ncnc(N)c12. References: Swaroop Vakkalankaa, et al. Inhibition of PI3Kdelta kinase by a selective, small molecule inhibitor suppresses B-cell proliferation and...

Keywords:	TGR-1202, RP5264, TGR 1202, TGR1202
Application:	Targets phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta
CAS	1532533-67-7
MW:	571.55 D

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TGR-1202

Item number: Cay32877-5

TGR-1202 is an inhibitor of PI3K p110delta (IC50 = 22 nM). It is selective for p110delta over p110alpha, p110beta, and p110gamma (IC50s = >10,000, 1,116, and 1,065 nM, respectively). TGR-1202 induces apoptosis in patient-derived chronic lymphocytic leukemia lymphocytes when used at concentrations ranging from 0.1 to...

Keywords:	RP 5264, Umbralisib,...
Application:	PI3K p110delta inhibitor
CAS	1532533-67-7
MW:	571.6 D

From 94.00€ *

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