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Item number: TGM-T4633-1mL

Description: Asimadoline (EMD-61753) is a proprietary small molecule therapeutic, originally discovered by Merck KGaA of Darmstadt, Germany. Asimadoline was originally developed to treat peripheral pain such as arthritis. Asimadoline is an orally administered agent that acts as a kappa opioid receptor agonist. It...

Keywords:	EMD-61753
Application:	kappa-opioid receptor (KOR) agonist
CAS	153205-46-0
MW:	414.54 D

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Asimadoline

Item number: Cay26411-1

Asimadoline is a potent kappa-opioid receptor (KOR) agonist (IC50s = 5.6 and 1.2 nM for guinea pig and human receptors, respectively). It is 501- and 498-fold selective for kappa-opioid over µ- and delta-opioid receptors, respectively. Asimadoline is spasmolytic in isolated rat duodenum (IC50 = 4.2 µM) and inhibits...

Keywords:	EMD 61753, N-[(1S)-2-[(3S)-3-hydroxy-1-pyrrolidinyl]-1-phenylethyl]-N-methyl-alpha-phenyl-benzeneacetamide
Application:	kappa-opioid receptor (KOR) agonist
CAS	153205-46-0
MW:	414.5 D

From 44.00€ *

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