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BC-1215
Item number: TGM-T5821-100mg
Description: BC-1215 is an inhibitor of F-box protein 3 (FBXO3, a ubiquitin E3 ligase component, IC50=0.9 µg/mL for IL-1beta release). Target: Others, Ligand for E3 Ligase. Smiles: C(CNCc1ccc(cc1)-c1ccccn1)NCc1ccc(cc1)-c1ccccn1. References: Bill B. Chen,Tiffany A. Coon,Jennifer R. Glasser,et, al. A combinatorial F...
| Application: | Fbxo3 inhibitor |
| CAS | 1507370-20-8 |
| MW: | 394.51 D |
From 46.00€
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BC-1215
Item number: Cay21964-1
BC-1215 is an inhibitor of F-box protein 3 (FBXO3, IC50 = 0.9 µg/mL for Il-1beta release). It decreases FBXO3 interaction with F-box/LRR-repeat protein 2 (FBXL2) in a dose-dependent manner and prevents FBXO3-dependent ubiquitination of FBXL2. It also lowers expression of Tnf receptor-associated factors (TRAFs) 1-6...
| Keywords: | N1,N2-bis[[4-(2-pyridinyl)phenyl]methyl]-1,2-ethanediamine |
| Application: | Fbxo3 inhibitor |
| CAS | 1507370-20-8 |
| MW: | 394.5 D |
From 55.00€
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