2 products were found matching "148849-67-6"!
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Ivabradine (hydrochloride)
Item number: Cay15868-10
Ivabradine is a hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker that blocks the mixed sodium/potassium inward funny current (If) in HEK293 cells expressing mouse HCN1, human HCN2, and human HCN4 (EC50s = 4.5, 4.52, and 4.28 µM, respectively). In vivo, ivabradine (10 mg/kg per day) reduces...
| Keywords: | S 16257,... |
| Application: | If (HCN1 / HCN2 / HCN4) channel blocker |
| CAS | 148849-67-6 |
| MW: | 505.1 D |
From 100.00€
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Ivabradine hydrochloride
Item number: TGM-T2535-100mg
Description: Ivabradine hydrochloride (S 16257-2) is a new If inhibitor (IC50: 2.9 µM). Ivabradine Hydrochloride is the hydrochloride salt form of ivabradine, an orally bioavailable, hyperpolarization-activated, cyclic nucleotide-gated (HCN) channel blocker, with negative chronotropic activity. Upon administration,...
| Keywords: | S 16257-2, Ivabradine HCl |
| Application: | Cardiotonic, HCN channel blocker |
| CAS | 148849-67-6 |
| MW: | 505.05 D |
From 34.00€
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