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Tyrphostin AG 879
Item number: TGM-T6712-100mg
Description: Tyrphostin AG 879 (AG 879) effectively inhibits HER2/ErbB2 with an IC50 of 1 µM, demonstrating 100- and 500-fold higher selectivity for ErbB2 over EGFR and PDGFR, respectively. Target: HER, EGFR, PDGFR, Apoptosis, Trk receptor. Smiles: CC(C)(C)c1cc(\C=C(/C#N)C(N)=S)cc(c1O)C(C)(C)C. References: Zhou...
| Keywords: | AG 879 |
| Application: | Tyrosine kinase inhibitor |
| CAS | 148741-30-4 |
| MW: | 316.46 D |
From 43.00€
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AG-879
Item number: Cay10793-5
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which selectively inhibit PTKs of key growth factors. AG-879 is a tyrphostin compound that inhibits nerve growth factor...
| Keywords: | Tyrphostin AG-879, 3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-cyano-2E-propenethioamide |
| Application: | Tyrosine kinase inhibitor |
| CAS | 148741-30-4 |
| MW: | 316.5 D |
From 93.00€
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