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L-732138
Item number: TGM-T8235-100mg
Description: L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM). Target: Neurokinin receptor. Smiles: CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1cc(cc(c1)C(F)(F)F)C(F)(F)F. References: Muñoz M, et al. The NK-1 Receptor Antagonist L-732,138 Induces Apoptosis and Counteracts...
| Application: | NK1 receptor antagonist |
| CAS | 148451-96-1 |
| MW: | 472.38 D |
From 31.00€
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L-732,138
Item number: Cay30894-10
L-732,138 is a neurokinin-1 (NK1) receptor antagonist (IC50 = 1.6 nM in CHO cells expressing the human receptor). It is selective for NK1 over NK2 and NK3 receptors (IC50s = >5,000 nM for both). L-732,138 inhibits the growth of COLO 858, MEL HO, and COLO 679 melanoma cells (IC50s = 44.6, 76.3, and 64.2 µM,...
| Keywords: | N-acetyl-L-tryptophan [3,5-bis(trifluoromethyl)phenyl]methyl ester |
| Application: | NK1 receptor antagonist |
| CAS | 148451-96-1 |
| MW: | 472.4 D |
From 85.00€
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