- Search results for 1477-19-6
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2 products were found matching "1477-19-6"!
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Item number: TGM-T20545-1g
Description: Benzarone (Benzarona) is a potent inhibitor of human uric acid transporter 1 (URAT1, IC50 = 2.8 µM in oocyte). Benzarone lowers the level of uric acid serum. Target: OAT. Smiles: CCc1oc2ccccc2c1C(=O)c1ccc(O)cc1. References: Kaufmann P, Török M, Hänni A, Roberts P, Gasser R, Krähenbühl S. Mechanisms of...
Keywords: | Benzaronum, Vasoc, Benzarona, Venagil |
Application: | Benzbromarone active metabolite |
CAS | 1477-19-6 |
MW: | 266.29 D |
From 30.00€
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Item number: Cay34903-1
Benzarone is an active metabolite of the urate anion transporter 1 (URAT1) inhibitor benzbromarone (Cay-19768). It inhibits URAT1 in Xenopus oocytes expressing the human enzyme (IC50 = 2.8 µM). Benzarone also inhibits the tyrosine phosphatase activity of eyes absent homolog 3 (EYA3, IC50 = 17.5 µM), as well as...
Keywords: | L 2197, NSC 82134, (2-ethyl-3-benzofuranyl)(4-hydroxyphenyl)-methanone |
Application: | Benzbromarone active metabolite |
CAS | 1477-19-6 |
MW: | 266.3 D |
From 61.00€
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