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Item number: TGM-T4050-100mg

Description: GSK2981278 (ROR gama modulator 1) is a highly potent and selective inverse agonist of retinoic acid receptor-related orphan receptor gamma (ROR gamma). Target: ROR. Smiles: CCc1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccc(OCC2CCOCC2)c(CO)c1. References: Birault Veronique, et al. Preparation of...

Keywords:	ROR gama modulator 1
Application:	Potent, selective ROR gamma inverse agonist
CAS	1474110-21-8
MW:	461.61 D

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GSK2981278

Item number: Cay20974-25

GSK2981278 is an inverse agonist of retinoic acid receptor-related nuclear receptor gamma (RORgamma, IC50 = 17 nM in a transactivation assay). It is selective for RORgamma over RORalpha. GSK2981278 inhibits IL-17A and IL-22 protein secretion from isolated human peripheral blood T cells grown under Th17 skewing...

Keywords:	N-(4-ethylphenyl)-3-(hydroxymethyl)-N-(2-methylpropyl)-4-[(tetrahydro-2H-pyran-4-yl)methoxy]-benzenesulfonamide
Application:	Potent, selective ROR gamma inverse agonist
CAS	1474110-21-8
MW:	461.6 D

From 52.00€ *

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