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Pyridostatin TFA
Item number: TGM-T4470-100mg
Description: Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-kit, K-ras and Bcl-2. Target: DNA/RNA Synthesis. Smiles: OC(=O)C(F)(F)F.NCCOc1cc(nc(c1)C(=O)Nc1cc(OCCN)c2ccccc2n1)C(=O)Nc1cc(OCCN)c2ccccc2n1....
| CAS | 1472611-44-1 |
| MW: | 938.71 D |
From 33.00€
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Pyridostatin (trifluoroacetate salt)
Item number: Cay18013-1
Pyridostatin is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome or the telomeres. It can compete for binding with the telomere-associated proteins and induce telomerase dysfunction. Pyridostatin induces DNA damage and cell cycle...
| Keywords: | 4-(2-aminoethoxy)-N2,N6-bis[4-(2-aminoethoxy)-2-quinolinyl]-2,6-pyridinedicarboxamide, trifluoroacetate salt |
| Application: | G-quadruplex stabilizer |
| CAS | 1472611-44-1 |
| MW: | 710.7 D |
From 43.00€
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Pyridostatin Trifluoroacetate Salt
Item number: LKT-P982691.10
Pyridostatin is a G-quadruplex ligand that induces conformation changes in telomere-G-quadruplex complexes and stimulates double-stranded DNA breakage, it also alters telomere function. Pyridostatin displays antiviral and anticancer activities. In vitro, this compound decreases synthesis of Epstein-Barr...
| Keywords: | Pyridostatin TFA salt, 4-(2-Aminoethoxy)-N2,N6-bis[4-(2-aminoethoxy)-2-quinolinyl]-2,6-pyridinedicarboxamide... |
| Application: | G-quadruplex ligand, Double-stranded DNA breakage stimulator |
| CAS | 1472611-44-1 |
| MW: | 710.67 D |
From 180.00€
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