- Search results for 147098-20-2
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4 products were found matching "147098-20-2"!
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Item number: TGM-T1510-100mg
Description: Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemic activity. Target: HMG-CoA Reductase, Potassium Channel, Autophagy. Smiles:...
Keywords: | ZD4522, ZD 4522 Calcium, Rosuvastatin hemicalcium |
Application: | Targets hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34] (HMGCR) |
CAS | 147098-20-2 |
MW: | 1001.14 D |
From 30.00€
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Item number: LKT-R5974.25
Statin, HMG-CoA reductase inhibitor, potential NADPH oxidase and PKC inhibitor.
Keywords: | (S-((R*,S*-(E)))- 7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2- (methyl(methylsulfonyl) amino)-5-pyrimidinyl)-3,5-dihydroxy-... |
Application: | HMGCoA reductase inhibitor |
CAS | 147098-20-2 |
MW: | 1001,14 D |
From 223.00€
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Item number: Cay18813-10
Rosuvastatin is an inhibitor of HMG-CoA reductase (IC50 = 5 nM). It inhibits cholesterol synthesis in isolated rat hepatocytes with an IC50 value of 0.16 nM. Rosuvastatin (10 mg/kg) reduces plasma total cholesterol, triglyceride, LDL-C, and oxidized LDL-C levels in Ldlr-/- mice fed a high-fat diet. It decreases the...
Keywords: | (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoi... |
Application: | HMG-CoA reductase inhibitor |
CAS | 147098-20-2 |
MW: | 500.6 D |
From 43.00€
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COVID-19 Research
Item number: AG-CR1-3728-M010
Soluble in DMSO (20mg/ml) or DMF (20mg/ml). Rosuvastatin is a potent competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme in the cholesterol biosynthetic pathway and the target of the statin class of cholesterol-lowering drugs. Rosuvastatin is antilipemic and is used to reduce plasma cholesterol...
Keywords: | ZD 4522, Crestor |
Application: | Antihyperlipidemic, HMG-CoA reductase inhibitor |
CAS | 147098-20-2 |
MW: | 500.6 D |
From 28.00€
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