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Cytarabine
Item number: Cay16069-10
Cytarabine (ara-C) is a nucleoside analog and prodrug form of the DNA polymerase inhibitor ara-CTP. It is triphosphorylated to ara-CTP by the successive actions of deoxycytidine kinase, deoxycytidylate kinase, and nucleoside diphosphate kinase. Ara-C inhibits proliferation of HL-60, ML-1, Raji, and Jurkat human...
| Keywords: | 1-beta-D-Arabinofuranosylcytosine, NSC 287459, NSC 63878, U-19920A, 4-amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone |
| Application: | Competitive DNA polymerase inhibitor |
| CAS | 147-94-4 |
| MW: | 243.2 D |
From 67.00€
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Cytarabine
Item number: TGM-T1272-200mg
Description: Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM). Cytarabine inhibits DNA polymerase and induces cell cycle arrest, autophagy, and apoptosis. Cytarabine has antitumor activity. Target: Endogenous Metabolite, Nucleoside Antimetabolite/Analog, HSV, Apoptosis,...
| Keywords: | Ara-C, Cytosine beta-D-arabinofuranoside, Arabinocytidine, Cytosine Arabinoside |
| Application: | Antineoplastic, Antimetabolite, DNA polymerase inhibitor |
| CAS | 147-94-4 |
| MW: | 243.22 D |
From 31.00€
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Cytarabine
Item number: LKT-C9778.1
Cytarabine is an antimetabolite compound which is proven to be one of the most effective agents available to treat leukemia. It induces its cytotoxic effect by inactivating DNA polymerases alpha, delta, and epsilon and consequently inhibit semi-conservative DNA replication and repair. It also has a potential to...
| Keywords: | Ara-C, Arabinofuranosyl Cytidine, cytosine arabinoside |
| Application: | DNA replication inhibitor |
| CAS | 147-94-4 |
| MW: | 243,22 D |
From 72.00€
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