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Item number: TGM-T15736-1mg

Description: Leriglitazone, a metabolite of pioglitazone, binds to the PPARgamma C-terminal ligand-binding domain (Ki: 1.2 µM) and induces transcriptional efficacy of the PPARgamma (EC50: 680 nM). Leriglitazone PioOH is a PPARgamma agonist, stabilizes the PPARgamma activation function-2 (AF-2) co-activator binding...

Keywords:	Hydroxypioglitazone
Application:	Targets peroxisome proliferator-activated receptor gamma (NR1C3, PPARG)
CAS	146062-44-4
MW:	372.44 D

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Hydroxy Pioglitazone

Item number: Cay28043-1

Hydroxy pioglitazone is a major metabolite of the peroxisome proliferator-activated receptor gamma (PPARgamma) agonist pioglitazone (Cay-71745, Cay-22263, Cay-10028). It is formed from pioglitazone by the cytochrome P450 (CYP) isoform CYP2C8 with minor contributions from CYP3A4. Hydroxy pioglitazone binds to...

Keywords:	5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione
Application:	Major metabolite
CAS	146062-44-4
MW:	372.4 D

From 376.00€ *

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