3 products were found matching "1454846-35-5"!
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Lorlatinib
Item number: TGM-T3061-100mg
Description: Lorlatinib (PF-6463922) is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene 1 (Ros1), with potential antineoplastic activity. Target: ROS, Apoptosis, ROS Kinase, Tyrosine Kinases, ALK. Smiles:...
| Keywords: | PF-06463922, Loratinib, PF-6463922 |
| Application: | Targets anaplastic lymphoma kinase [EC:2.7.10.1] (ALK, CD246) |
| CAS | 1454846-35-5 |
| MW: | 406.41 D |
From 37.00€
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PF-06463922
Item number: Cay18371-1
Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase that promotes cell proliferation and blocks apoptosis. PF-06463922 is an ATP-competitive, selective inhibitor of ALK (Ki = i = 0.7 nM). It has strong activity against all known ALK and ROS1 mutants identified in patients, including the EML4-L1196M mutant...
| Keywords: | Lorlatinib,... |
| Application: | ALK / ROS1 inhibitor |
| CAS | 1454846-35-5 |
| MW: | 406.4 D |
From 52.00€
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Lorlatinib
Item number: LKT-L582694.5
| Keywords: | PF-6463922, PF-06463922,... |
| Application: | ALK / ROS1 inhibitor |
| CAS | 1454846-35-5 |
| MW: | 406.21 D |
From 128.00€
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