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Item number: TGM-T4051-1mg

Description: LDC4297 (LDC044297) is a potent and selective CDK7 inhibitor. Target: CDK, HSV. Smiles: CC(C)c1cnn2c(NCc3ccccc3-n3cccn3)nc(OC3CCCNC3)nc12. References: Hutterer C, et al. A novel CDK7 inhibitor of the Pyrazolotriazine class exerts broad-spectrum antiviral activity at nanomolar concentrations. Antimicrob...

Keywords:	LDC044297
Application:	CDK7 inhibitor
CAS	1453834-21-3
MW:	432.52 D

49.00€ *

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LDC-4297

Item number: Cay23398-1

LDC-4297 is an inhibitor of cyclin-dependent kinase 7 (CDK7, IC50 = 50s = >10, >10, and 1.71 µM), however, it also inhibits CDK2 and CDK1 (IC50s = 6.4 and 53.7 nM, respectively). LDC-4297 (10-100 nM) induces apoptosis in A549, HeLa, and HCT116 cancer cells in a concentration-dependent manner. It inhibits human...

Keywords:	8-(1-methylethyl)-2-(3-piperidinyloxy)-N-[[2-(1H-pyrazol-1-yl)phenyl]methyl]-pyrazolo[1,5-a]-1,3,5-triazin-4-amine
Application:	CDK7 inhibitor
CAS	1453834-21-3
MW:	432.5 D

From 52.00€ *

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