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Item number: TGM-T16859-100mg

Description: SBI-425 is an effective and orally bioavailable inhibitor of tissue-nonspecific alkaline phosphatase (TNAP). SBI-425 effectively inhibits TNAP in the vasculature and improves cardiovascular parameters and survival without a detectable change in the bone. Target: Others. Smiles:...

Application:	TNAP inhibitor
CAS	1451272-71-1
MW:	341.77 D

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SBI-425

Item number: Cay34626-1

SBI-425 is an inhibitor of tissue-nonspecific alkaline phosphatase (TNAP, IC50 = 0.016 µM). It is selective for TNAP over a panel of 35 targets at 10 µM. SB-425 (10 and 30 mg/kg) increases survival and nearly completely inhibits the development of medial arterial calcification in a mouse model of chronic kidney...

Keywords:	5-[[(5-chloro-2-methoxyphenyl)sulfonyl]amino]-3-pyridinecarboxamide
Application:	TNAP inhibitor
CAS	1451272-71-1
MW:	341.8 D

From 45.00€ *

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