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Item number: Cay30108-1

MLN7243 is an inhibitor of ubiquitin-activating enzyme (UAE, IC50 = 1 nM). It is selective for UAE over NEDD8-activating enzyme (NAE), SUMO-activating enzyme (SAE), and the autophagy-activating enzyme ATG7 (IC50s = 28, 850, and >10,000 nM, respectively). MLN7243 inhibits proliferation in a panel of 30 cancer cell...

Keywords:	TAK-243, sulfamic acid,...
Application:	Ubiquitin-like modifier-activating enzyme 1 (UBA1) inhibitor
CAS	1450833-55-2
MW:	519.5 D

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