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AZD3965
Item number: TGM-T3210-10mg
Description: AZD3965 (AZD-3965) is a selective inhibitor of monocarboxylate transporter 1 (MCT1). Target: Monocarboxylate transporter. Smiles: CC(C)n1c2sc(Cc3c(C)[nH]nc3C(F)(F)F)c(C(=O)N3C[C@](C)(O)CO3)c2c(=O)n(C)c1=O. References: Critchlow SE, et al. 2012. AACR 103rd Annual Meeting.
| Keywords: | AZD 3965, AZD-3965 |
| Application: | SLC16A1 inhibitor |
| CAS | 1448671-31-5 |
| MW: | 515.51 D |
From 50.00€
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AZD 3965
Item number: Cay19912-1
AZD 3965 is a potent inhibitor of monocarboxylate transporter 1 (MCT1, Ki = 1.6 nM), killing tumor cells that are reliant on glycolysis by blocking lactate transport. It displays six-fold selectivity for MCT1 over MCT2 and is without effect against MCT4 at 10 µM. AZD 3965 increases intratumor lactate levels and...
| Keywords: | 5-[[(4S)-4-hydroxy-4-methyl-2-isoxazolidinyl]carbonyl]-3-methyl-1-(1-methylethyl)-6-[[5-methyl-3-(trifluoromethyl)-1H-pyra... |
| Application: | SLC16A1 inhibitor |
| CAS | 1448671-31-5 |
| MW: | 515.5 D |
From 66.00€
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