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SP-13786
Item number: Cay41857-10
SP-13786 is an inhibitor of the protease fibroblast activation protein (FAP, IC50 = 3.2 nM). It is selective for FAP over prolyl endopeptidase, dipeptidyl peptidase 4 (DPP-4), DPP-9, and DPP-2 (IC50s = >1.8, >100, >12.5, and >100 µM, respectively). Nanoliposomes containing a PEGylated form of SP-13786 have been used...
| Keywords: | UAMC-1110, N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-4-quinolinecarboxamide |
| Application: | FAP inhibitor |
| CAS | 1448440-52-5 |
| MW: | 344.3 D |
From 126.00€
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SP-13786
Item number: TGM-T7890-100mg
Description: SP-13786 (UAMC-1110) is an inhibitor of fibroblast activation protein (FAP) (IC50 : 3.2 nM), also inhibits prolyl oligopeptidase (PREP) ( IC50 : 1.8 µM). Target: Others. Smiles: C(NCC(=O)N1[C@H](C#N)CC(F)(F)C1)(=O)C=2C3=C(N=CC2)C=CC=C3. References: Jansen K , Heirbaut L , Verkerk R , et al. Extended...
| Keywords: | UAMC-1110 |
| CAS | 1448440-52-5 |
| MW: | 344.32 D |
From 66.00€
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