3 products were found matching "1448428-05-4"!
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Selonsertib HCl
Item number: TGM-T70622-100mg
Description: Selonsertib, also known as GS-4997, is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. GS-4997 targets and binds to the catalytic kinase domain of ASK1 in an ATP-competitive manner, thereby...
| Application: | pan-RAF inhibitor |
| CAS | 1448428-05-4 |
| MW: | 481.96 D |
From 1,971.00€
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Selonsertib Hydrochloride
Item number: SYN-1229-M001
Solid. Soluble in DMSO or ethanol. LY2784544 is a potent JAK2 inhibitor with IC(50) of 3nM, effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3. Phase 2.
| Keywords: | LY-2784544 |
| Application: | JAK2 inhibitor |
| CAS | 1448428-05-4 |
| MW: | 469,9 D |
From 139.00€
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BIX02565
Item number: SYN-1228-M100
Solid. Soluble in DMSO or ethanol. Slightly soluble (<1mg/ml) in water. TAK-632 is a potent pan-RAF inhibitor with favorable in vitro activity (BRAF(V600E) IC(50) of 2.4nM.
| Keywords: | TAK632 |
| Application: | pan-RAF inhibitor |
| CAS | 1448428-05-4 |
| MW: | 554,5 D |
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