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Item number: TGM-T3617-100mg

Description: Ivosidenib (AG-120) is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1) with potential antineoplastic activity. It specifically inhibits a mutated form of IDH1 in the cytoplasm, preventing the formation of the oncometabolite 2-hydroxyglutarate (2 hG), which may induce cellular...

Keywords:	AG-120
Application:	Targets isocitrate dehydrogenase [EC:1.1.1.42] (IDH1, IDH2, icd)
CAS	1448347-49-6
MW:	582.96 D

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AG-120

Item number: Cay19894-10

AG-120 is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1) that specifically inhibits a mutated form of IDH1 in the cytoplasm, preventing the formation of 2-hydroxyglutarate. AG-120 may induce cellular differentiation as well as inhibit proliferation in IDH1-expressing tumor cells.Formal Name:...

Keywords:	Invosidenib,...
Application:	IDH1 inhibitor
CAS	1448347-49-6
MW:	583 D

From 44.00€ *

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