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Item number: Cay21277-1

Enasidenib is an inhibitor of mutant isocitrate dehydrogenase 2 (IDH2, IC50 = 0.1 µM for IDH2 R140Q). It is selective for IDH2 R140Q over wild-type IDH2, wild-type IDH1, and IDH1 R132H (IC50s = 1.8, 0.45, and 48.4 µM, respectively). Enasidenib (0.1, 1, and 5 µM) inhibits production of D-2-hydroxyglutarate...

Keywords:	AG-221, CC-90007,...
Application:	Allosteric IDH2 inhibitor
CAS	1446502-11-9
MW:	473.4 D

34.00€ *

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Enasidenib

Item number: Cay21277-10

Keywords:	AG-221, CC-90007,...
Application:	Allosteric IDH2 inhibitor
CAS	1446502-11-9
MW:	473.4 D

From 68.00€ *

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