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Lu AF21934
Item number: TGM-T3539-100mg
Description: Lu AF21934 is a brain-penetrant and selective mGlu4 receptor positive allosteric modulator (IC50: 500 nM, human). Target: GluR. Smiles: NC(=O)[C@@H]1CCCC[C@@H]1C(=O)Nc1ccc(Cl)c(Cl)c1. References: Slawinska A, et al. Anxiolytic- but not antidepressant-like activity of Lu AF21934, a novel, selective...
| Application: | mGluR4 positive allosteric modulator (PAM) |
| CAS | 1445605-23-1 |
| MW: | 315.2 D |
From 35.00€
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Lu AF21934
Item number: Cay27045-1
Lu AF21934 is a positive allosteric modulator (PAM) of metabotropic glutamate receptor 4 (mGluR4, EC50 = 500 nM for the human receptor in a FLIPR assay). It is selective for mGluR4 over mGluR6 (EC50 = 7 µM) and a panel of 73 CNS ion channels, G protein-coupled receptors (GPCRs), and enzymes at 10 µM. Lu AF21934 (12...
| Keywords: | N1-(3,4-dichlorophenyl)-1S,2R-cyclohexanedicarboxamide |
| Application: | mGluR4 positive allosteric modulator (PAM) |
| CAS | 1445605-23-1 |
| MW: | 315.2 D |
From 61.00€
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