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Tirabrutinib hydrochloride
Item number: TGM-T12311-100mg
Description: Tirabrutinib hydrochloride (GS-4059 (hydrochloride)) is a selective and novelBTK with IC50 2.2 nm inhibitor. Target: BTK. Smiles: Cl.CC#CC(=O)N1CC[C@H](C1)n1c2ncnc(N)c2n(-c2ccc(Oc3ccccc3)cc2)c1=O. References: Akintunde Akinleye et al. Ibrutinib and novel BTK inhibitors in clinical development. J Hematol...
| Keywords: | ONO-4059 (hydrochloride), GS-4059 (hydrochloride) |
| Application: | Targets Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2] (BTK) |
| CAS | 1439901-97-9 |
| MW: | 490.94 D |
From 31.00€
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ONO-4059 (hydrochloride)
Item number: Cay32818-10
ONO-4059 is an inhibitor of Bruton's tyrosine kinase (BTK, IC50 = 2.2 nM). It is selective for BTK over LCK, LYN, and Fyn at 1 µM. ONO-4059 inhibits B cell proliferation and activation in vitro and reduces tumor growth in a TMD8 mouse xenograft model.Formal Name:...
| Keywords: | GS-4059, ONO-WG-307,... |
| Application: | BTK inhibitor |
| CAS | 1439901-97-9 |
| MW: | 490.9 D |
From 150.00€
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