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Item number: TGM-T3511-100mg

Description: PF-1355 (PF 06281355) is a selective 2-thiouracil mechanism-based MPO inhibitor. PF-1355 is used for treatment of vasculitic diseases. Target: Glutathione Peroxidase. Smiles: COc1ccc(OC)c(c1)-c1cc(=O)[nH]c(=S)n1CC(N)=O. References: Zheng W, et al. PF-1355, a mechanism-based myeloperoxidase inhibitor,...

Keywords:	PF 06281355, PF-06281355, ZINC205721785
Application:	MPO inhibitor
CAS	1435467-38-1
MW:	321.35 D

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PF-1355

Item number: Cay22222-1

PF-1355 is an irreversible myeloperoxidase (MPO) inhibitor (Ki = 346.74 nM in a cell-free assay). It is selective for MPO over thyroid peroxidase (TPO) and over a panel of more than 50 enzymes, receptors, transporters, and ion channels. It inhibits MPO activity in isolated human whole blood with an IC50 value of 1.5...

Keywords:	PF-06281355, 6-(2,5-dimethoxyphenyl)-3,4-dihydro-4-oxo-2-thioxo-1(2H)-pyrimidineacetamide
Application:	MPO inhibitor
CAS	1435467-38-1
MW:	321.4 D

From 44.00€ *

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