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Pregnenolone Carbonitrile
Pregnenolone Carbonitrile

Item number: Cay16343-25

Pregnenolone carbonitrile (PCN) is a catatoxic steroid that acts as an agonist of the rodent pregnane X receptor (PXR) at µM concentrations. It has been shown to mediate induction of hepatic cytochrome P450 3A, organic anion transporting peptide-2, and cholesterol 7alpha-hydroxylase, regulating both xenobiotic and...
Keywords: PCN, Pregnenolone 16alpha-carbonitrile, SC-4674, 3beta-hydroxy-20-oxo-pregn-5-ene-16alpha-carbonitrile
Application: Rodent pregnane X receptor (PXR) agonist
CAS 1434-54-4
MW: 341.5 D
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