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SAR131675
Item number: TGM-T6012-100mg
Description: SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM. Target: VEGFR. Smiles: C(C)N1C=2C(C(=O)C(C(NC)=O)=C1N)=CC=C(C#C[C@@](COC)(C)O)N2. References: Alam A, et al. SAR131675, a potent and selective VEGFR-3-TK inhibitor with antilymphangiogenic, antitumoral, and antimetastatic...
| Keywords: | SAR 131675 |
| Application: | VEGFR3 inhibitor |
| CAS | 1433953-83-3 |
| MW: | 358.39 D |
From 31.00€
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SAR131675
Item number: Cay28385-1
SAR131675 is an ATP-competitive inhibitor of VEGF receptor 3 (VEGFR3) with an IC50 value of 23 nM for the human recombinant receptor in a cell-free assay. It is selective for VEGFR3 over VEGFR2 and VEGFR1 (IC50s = 230 and >3,000 nM, respectively). SAR131675 inhibits survival of human lymphatic cells cultured with...
| Keywords: | 2-amino-1-ethyl-1,4-dihydro-7-[(3R)-3-hydroxy-4-methoxy-3-methyl-1-butyn-1-yl]-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide |
| Application: | VEGFR3 inhibitor |
| CAS | 1433953-83-3 |
| MW: | 358.4 D |
From 43.00€
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