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ORY1001
ORY1001

Item number: TGM-T6922-100mg

Description: ORY1001 (ORY 1001) is an orally active and selective lysine-specific demethylase LSD1/KDM1A inhibitor, with high selectivity against related FAD dependent aminoxidases with IC50 of <20 nM. Target: Histone Demethylase. Smiles: Cl.Cl.NC1CCC(CC1)N[C@@H]1C[C@H]1c1ccccc1. References: Maes T, et al. J Clin...
Keywords: RG-6016, ORY-1001 (RG-6016) 2HCl, ORY-1001, ORY 1001
Application: LSD1 inhibitor
CAS 1431326-61-2
MW: 303.27 D
From 55.00€ *
Review
ORY-1001
ORY-1001

Item number: Cay19136-1

ORY-1001 is an inhibitor of lysine-specific demethylase 1 (LSD1), an oxidase that demethylates histone 3 at lysine 4 (H3K4) and H3K9 (IC50 = 0.018 µM). It is selective for LSD1 over LSD2, monoamine oxidase A (MAO-A), and MAO-B (IC50s = >100 µM) but does inhibit spermine oxidase (IC50 = 7.4 µM). ORY-1001 also...
Keywords: RG-6016, rel-N1-[(1R,2S)-2-phenylcyclopropyl]-1,4-cyclohexanediamine, dihydrochloride
Application: LSD1 inhibitor
CAS 1431326-61-2
MW: 303.3 D
From 44.00€ *
Review