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Item number: TGM-T7611-100mg

Description: ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity. Target: VEGFR, FGFR. Smiles: Cn1cc(cn1)-c1ccc2n(cnc2c1)-c1cc(NS(=O)(=O)C2CC2)cc(c1)-c1ccc(F)cc1F. References: Tim H Holmström , Anu-Maarit Moilanen , Tarja Ikonen,et al.ODM-203, a...

Application:	VEGFR / FGFR dual inhibitor
CAS	1430723-35-5
MW:	505.54 D

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ODM-203

Item number: Cay31451-10

ODM-203 is a dual inhibitor of VEGFR and FGFR (IC50s = 5-26 and 6-35 nM for VEGFR1-3 and FGFR1-4, respectively). It is selective for VEGFR1-3 and FGFR1-4 over a panel of 308 kinases at 1 µM, but does inhibit the receptor tyrosine kinases PDGFRalpha, PDGFRbeta, and DDR1 (IC50s = 35, 169, and 6 nM, respectively), as...

Keywords:	N-[2',4'-difluoro-5-[5-(1-methyl-1H-pyrazol-4-yl)-1H-benzimidazol-1-yl][1,1'-biphenyl]-3-yl]-cyclopropanesulfonamide
Application:	VEGFR / FGFR dual inhibitor
CAS	1430723-35-5
MW:	505.5 D

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