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Item number: TGM-T2683-10mg

Description: IWP L6 (Porcn Inhibitor III) is a highly potent Porcn inhibitor with an EC50 of 0.5 nM. Target: Porcupine. Smiles: O=C(CSc1nc2CCSc2c(=O)n1-c1ccccc1)Nc1ccc(cn1)-c1ccccc1. References: Wang X, et al. J Med Chem. 2013, 56(6), 2700-2704.

Keywords:	Porcn Inhibitor III, IWP-L6, Porcn Inhibitor III
CAS	1427782-89-5
MW:	472.58 D

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IWP-L6

Item number: Cay15243-5

Porcupine (PORCN) is a membrane bound O-acyltransferase that mediates palmitoylation of Wnt family proteins. This step is required for secretion and biologic activity of Wnt proteins, which have roles in embryonic development and cancer. IWP-L6 is a potent inhibitor of PORCN (EC50 = 0.5 nM). It suppresses the...

Keywords:	PORCN Inhibitor III, Wnt Pathway Inhibitor XIX,...
Application:	Potent PORCN inhibitor
CAS	1427782-89-5
MW:	472.6 D

From 112.00€ *

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