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ML299
Item number: TGM-T8968-1mg
Description: ML299 (VU0463568) is a dual PLD1/2 inhibitor (PLD1 and PLD2, IC50 of 6 nM, 20 nM, respectively). Target: Phospholipase. Smiles: C[C@@H](CN1CCC2(CC1)N(CNC2=O)c1cccc(F)c1)NC(=O)c1ccc(Br)cc1
| Keywords: | VU0463568, ML-299 |
| Application: | PLD1 / PLD2 inhibitor |
| CAS | 1426916-00-8 |
| MW: | 489.38 D |
From 142.00€
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ML-299
Item number: Cay17632-1
ML-299 is a dual inhibitor of phospholipase D1 (PLD1) and PLD2 (IC50s = 6 and 20 nM, respectively). It is selective for PLD1 and PLD2 over a panel of 65 receptors but also inhibits human-ether-a-go-go (hERG), also known as Kv11.1, as well as kappa- and µ-opioid receptors at 10 µM. ML-299 (1 and 10 µM) decreases...
| Keywords: | CID 56593087, 4-bromo-N-[(1S)-2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]-1-methylethyl]-benzamide |
| Application: | PLD1 / PLD2 inhibitor |
| CAS | 1426916-00-8 |
| MW: | 489.4 D |
From 78.00€
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