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Gusacitinib
Item number: LKT-G823720.100
Gusacitinib is a dual inhibitor of SYK/JAK kinases. SMILES: C1CN(CCC1CC#N)C2=NC3=C(C(=O)NN=C3)C(=N2)NC4=CC=C(C=C4)N5CCC(CC5)O
| Keywords: | ASN-002, ASN002,... |
| Application: | SYK/JAK inhibitor |
| CAS | 1425381-60-7 |
| MW: | 460.54 D |
From 115.00€
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Gusacitinib
Item number: TGM-T14331-100mg
Description: Gusacitinib (ASN-002) (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM). Target: JAK, Syk. Smiles: OC1CCN(CC1)c1ccc(Nc2nc(nc3cn[nH]c(=O)c23)N2CCC(CC#N)CC2)cc1. References: Sanjeeva Reddy, et al. Abstract 792: ASN002: A novel dual SYK/JAK inhibitor with strong...
| Keywords: | ASN-002 |
| Application: | Targets Janus kinase 1 [EC:2.7.10.2] (JAK1) |
| CAS | 1425381-60-7 |
| MW: | 460.53 D |
From 37.00€
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Gusacitinib
Item number: Cay36554-1
Gusacitinib is a dual inhibitor of JAKs (IC50s = 46, 4, and 11 nM for JAK1-3, respectively) and Syk family kinases (IC50s = 5 and 8 nM for SyK and TYK2, respectively).Formal Name: 1-[5,6-dihydro-4-[[4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5-oxopyrimido[4,5-d]pyridazin-2-yl]-4-piperidineacetonitrile. CAS Number:...
| Keywords: | ASN-002,... |
| Application: | JAK / Syk family kinase dual inhibitor |
| CAS | 1425381-60-7 |
| MW: | 460.5 D |
From 40.00€
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