2 products were found matching "1422253-38-0"!
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PRI-724
Item number: Cay41728-10
PRI-724 is a prodrug form of the beta-catenin/CREB-binding protein (CBP) inhibitor C-82 and a derivative of ICG-001 (Cay-16257). It is cytotoxic to GES-1 gastric mucosal and HGC-27, MKN45, and AGS gastric cancer cells (IC50s = 16.53, 9.8, 44.28, and 3.48 µM, respectively) and enhances decreases in viability induced...
| Keywords: | (6S,9S,9aS)-hexahydro-2,9-dimethyl-4,7-dioxo-N-(phenylmethyl)-6-[[4-(phosphonooxy)phenyl]methyl]-8-(8-quinolinylmethyl)-2H... |
| Application: | C-82 (CREB-binding protein inhibitor) prodrug |
| CAS | 1422253-38-0 |
| MW: | 658.7 D |
From 75.00€
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PRI-724
Item number: TGM-T64414-100mg
Description: PRI-724 (C-82 prodrug) is a selective small-molecule inhibitor of beta-catenin/CBP interaction. Target: Wnt/beta-catenin. Smiles: C([C@@H]1N2[C@@](N(C(NCC3=CC=CC=C3)=O)N(C)CC2=O)([C@H](C)N(CC=4C5=C(C=CC4)C=CC=N5)C1=O)[H])C6=CC=C(OP(=O)(O)O)C=C6. References: PRI-724 reduces liver fibrosis, and hepatic...
| Keywords: | Foscenvivint, ICG-001 analog, C-82 prodrug |
| Application: | Targets catenin beta 1 (CTNNB1) |
| CAS | 1422253-38-0 |
| MW: | 658.64 D |
From 42.00€
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