3 products were found matching "1421373-65-0"!
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AZD 9291
Item number: Cay16237-10
AZD 9291 is an inhibitor of mutant EGFRs (IC50s = 1, 12, and 5 nM for EGFRL858R/T790M, EGFRL858R, and EGFRL861Q, respectively). It is selective for these mutant EGFRs over wild-type EGFR (IC50 = 184 nM), as well as over a panel of approximately 280 other kinases at 1 µM. AZD 9291 selectively inhibits the...
| Keywords: | Osimertinib,... |
| Application: | Mutant-selective EGFR inhibitor |
| CAS | 1421373-65-0 |
| MW: | 499.6 D |
From 44.00€
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AZD-9291
Item number: LKT-A985134.100
EGFR inhibitor.
| Keywords: | AZD 9291, AZD9291, Osimertinib, Mereletinib |
| Application: | Mutant-selective EGFR inhibitor |
| CAS | 1421373-65-0 |
| MW: | 499.62 D |
From 123.00€
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Osimertinib
Item number: TGM-T2490-100mg
Description: Osimertinib (AZD-9291) is an EGFR third-generation inhibitor that inhibits the T790M resistance mutation produced by second-generation EGFR inhibitors with irreversible and oral activity. Osimertinib has antitumor activity for the treatment of EGFR-mutated non-small-cell lung cancer. Target: EGFR....
| Keywords: | Mereletinib, AZD-9291 |
| Application: | Mutant-selective EGFR inhibitor |
| CAS | 1421373-65-0 |
| MW: | 499.61 D |
From 33.00€
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