3 products were found matching "1420477-60-6"!
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Acalabrutinib
Item number: TGM-T3626-100mg
Description: Acalabrutinib (ACP-196), also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. Upon administration, ACP-196 inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. This...
| Keywords: | ACP-196 |
| Application: | Targets Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2] (BTK) |
| CAS | 1420477-60-6 |
| MW: | 465.51 D |
From 41.00€
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Acalabrutinib
Item number: Cay19899-5
Acalabrutinib is an irreversible inhibitor of Bruton's tyrosine kinase (BTK). It can dose-dependently inhibit B cell receptor signaling in primary chronic lymphocytic leukemia cells. In kinase-inhibition assays, acalabrutinib was more selective than ibrutinib (Cay-16274) for inhibiting BTK and did not inhibit EGFR,...
| Keywords: | ACP-196, 4-[8-amino-3-[(2S)-1-(1-oxo-2-butyn-1-yl)-2-pyrrolidinyl]imidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinyl-benzamide |
| Application: | BTK inhibitor |
| CAS | 1420477-60-6 |
| MW: | 465.5 D |
From 44.00€
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Acalabrutinib
Item number: LKT-A081014.100
| Keywords: | ACP-196 |
| Application: | BTK inhibitor |
| CAS | 1420477-60-6 |
| MW: | 465.52 D |
From 161.00€
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