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Item number: TGM-T12490-10mg

Description: Pitavastatin lactone is the major metabolite of Pitavastatin in humans.Pitavastatin is a competitive inhibitor of HMG-CoA reductase. Target: HMG-CoA Reductase, Others. Smiles: C(=C/[C@@H]1C[C@@H](O)CC(=O)O1)\C2=C(C3=C(N=C2C4CC4)C=CC=C3)C5=CC=C(F)C=C5. References: Fujino H, et al. Metabolic fate of...

Application:	HMG-CoA reductase inhibitor
CAS	141750-63-2
MW:	403.45 D

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Pitavastatin lactone

Item number: Cay21785-1

Pitavastatin lactone is a major phase 2 metabolite of the HMG-CoA reductase inhibitor pitavastatin (Cay-15414). Pitavastatin lactone is formed when pitavastatin undergoes glucuronidation by the UDP-glucuronysyltransferase (UGT) isoforms UGT1A1, UGT1A3, or UGT2B7 to form pitavastatin glucuronide, which then undergoes...

Keywords:	6S-[(1E)-2-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]tetrahydro-4R-hydroxy-2H-pyran-2-one
Application:	HMG-CoA reductase inhibitor
CAS	141750-63-2
MW:	403.5 D

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